Acceleration of diels-alder reactions by remote methyl groups
نویسندگان
چکیده
منابع مشابه
Appendix 1. Diels-Alder Reactions
One of the most efficient methods (high yield, controlled stereochemistry, diverse functionality) to construct rings from smaller fragments is via cycloaddition reactions. The reverse reaction, namely splitting of a ring into smaller fragments is termed a cycloreversion reaction is also an important synthetic tool. (For example, in the present experiment it is the cracking of cyclopentadiene di...
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This review illustrates how water, as an environmentally friendly solvent, can have significant additional benefits when it is used as a solvent for the Diels–Alder reaction. The mechanism by which the unique properties of water enhance the rate and selectivity are discussed. Also, possibilities for the achievement of further increases in rate and enantioselectivity of aqueous Diels–Alder react...
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The Diels-Alder reaction has often been used to construct polycyclic quinones from either benzoquinones or naphthoquinones.' This strategy has led to elegant syntheses of certain anthracyclines and also many other acetate-derived compounds. Several researchers, most notably Gesson and Brassard, have determined that the presence of a chlorine or bromine atom on the starting quinone framework per...
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The synthesis of silaheterocycles through the first examples of an intramolecular silene Diels-Alder reaction is described.
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Like molecules of life (e.g., proteins and DNA), many pharmaceutical drugs are also asymmetric (chiral); they are not superimposable on their mirror images. One mirror image form (enantiomer) of a drug can have desirable activity, the other not. Consequently, the development of methods for the selective synthesis of one enantiomer is of great scientific and economic importance. We report here t...
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ژورنال
عنوان ژورنال: Tetrahedron
سال: 1989
ISSN: 0040-4020
DOI: 10.1016/s0040-4020(01)81013-9